Hepatic impairment, biliary obstruction or disease. Monitor hepatic function periodically in patients on high or prolonged oral doses. Avoid use during 3rd trimester of pregnancy. Lactation. Premature, jaundiced, acidotic or seriously ill neonates.
Adverse Reactions
GI disturbances eg, dyspepsia, nausea, vomiting, epigastric pain, anorexia; jaundice & change of liver function.